DNA replication and human disease

At least 5 trillion cell divisions are required for a fertilized egg to develop into an adult human, resulting in the production of more than 20 trillion meters of DNA! And yet, with only two exceptions, the genome is replicated once and only once each time a cell divides. How is this feat accomplished? What happens when errors occur? This book addresses these questions by presenting a thorough analysis of the molecular events that govern DNA replication in eukaryotic cells. The association between genome replication and cell proliferation, disease pathogenesis, and the development of targeted therapeutics is also addressed.

שנה

2006

שפה

English

סדרה

Cold Spring Harbor monograph series -- 46

הוצאה

Cold Spring Harbor Laboratory Press

מהדורות

1

עמודים

814

ISBN

9780879697662

מקור הנתונים: Wikidata