Hypocretins as integrators of physiological signals

The hypocretins (orexins) are a newly identified (1998) peptide family comprised of two peptides, hypocretin-1 and hypocretin-2. Recent observations suggest an involvement of these peptides, located primarily in the hypothalmus, in the regulation of behavioral state. They are involved in circadian rhythms, metabolism, hormone secretion, body temperature, appetite, cardiovascular functions (e.g., blood pressure), and sleep abnormalities (e.g., narcolepsy and cataplexy).

שנה

2005

שפה

English

הוצאה

Springer

מהדורות

1

עמודים

439

ISBN

9780387250007

מקור הנתונים: Wikidata