Alpha 1 - Antitrypsin Deficiency (Lung Biology in Health and Disease)

"Providing a broad overview of basic and clinical aspects of alpha 1-antitrypsin ([alpha]1AT) deficiency, this up-to-date reference discusses the complex pathobiological processes underlying the pathogenesis of [alpha]1AT deficiency, describes the [alpha]1AT gene and its promoter, and details specific therapies to prevent the major clinical manifestations of the disorder." "Containing authoritative contributions from more than 35 leading experts in their respective fields, Alpha 1-Antitrypsin Deficiency considers the treatment of [alpha]1AT deficiency with [alpha]1AT replacement therapy ... reviews current literature on the expression and regulation of the [alpha]1AT gene in mononuclear phagocytes in normal and deficient individuals ... analyzes pulmonary function data supporting the development of premature emphysema in people with [alpha]1AT deficiency ... elucidates the theoretical and experimental basis for the modern conception of the role of proteases and anti-proteases in reactive airways disease ... examines the goals and design of the Registry for Patients with Severe Deficiency of Alpha 1-Antitrypsin sponsored by the National Heart, Lung and Blood Institute ... surveys the status of lung transplantation for antitrypsin-deficiency emphysema ... and more."--Jacket.

Year

1995

Language

English

Publisher

Informa Healthcare

Editions

1

Pages

472

ISBN

9780824788483

Data source: Wikidata