Role of Capsaicin in Oxidative Stress and Cancer
Sanjay K. Srivastava · 2013
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This book describes the mechanism of the anti-cancer effects of capsaicin including the involvement of cytochrome P-450 in the bioactivation; identification of mitochondria as the key target site for oxidative stress; involvement of mitochondrial respiratory chain in the production of ROS; prevention of chemically-induced carcinogenesis, discussion on TRPV-1 receptor mediated or independent anti-cancer effects; identification of p53 activation as a possible mechanism; involvement of Cox-2 in apoptosis, suppression of transcription factors such as NF-kB and STAT-3; inhibition of cell survival p
Book details
- Year
- 2013
- Language
- English
- Publisher
- Springer London, Limited
- Editions
- 4
- Pages
- 178
- ISBN
- 9789400763173
Data source: Wikidata